Maternal folate levels may predict risk of childhood overweight or obesity

Adequate maternal folate levels may mitigate the risk for childhood obesity, especially among children born to obese mothers, according to a prospective birth cohort study conducted at the Boston Medical Center, Boston, Massachusetts and published online June 13, 2016 in JAMA Pediatrics. The highest risk for child overweight or obesity was found among children of obese mothers with low folate concentrations. The authors suggest that there is a need to establish optimal rather than minimal folate concentrations for preventing adverse metabolic outcomes in the offspring.