Concomitant administration of flu vaccine with other vaccines increases risk of febrile seizures

Review of data from the CDC’s Vaccine Data Safetylink program published online June 06, 2016 in the journal Pediatrics finds that the administration of trivalent inactivated influenza vaccine (IIV3) on the same day as either pneumococcal conjugate vaccine (PCV) or a diphtheria-tetanus-acellular-pertussis (DTaP)-containing vaccine was associated with a greater risk of febrile seizures than when IIV3 was given on a separate day. Risk increased 5-fold when all three vaccines were administered together than when given separately.