Children with Down’s syndrome prone to arthropathy

Children with Down’s syndrome should have an annual musculoskeletal examination because of their increased risk of developing arthritis, an association that is widely unrecognized. The prevalence is higher than that of juvenile idiopathic arthritis (JIA), at 8.7/1,000 compared with 1/1,000 according to a study presented at the annual meeting of the British Society for Rheumatology held in Glasgow, UK. The Down’s arthropathy group also more commonly had involvement of the small joints (88% versus 43%, P<0.01) and specifically of the proximal interphalangeal joints, which were affected in 78.6% of the Down’s arthropathy group.